1368 Does mitochondrial dysfunction drive immune privilege collapse in lichen planopilaris pathogenesis?
نویسندگان
چکیده
منابع مشابه
Lichen Planopilaris After Hair Transplantation
Hair transplantation (HT) is highly effective in secondary cicatricial alopecias such as after thermal burns, trauma, or radiotherapy-induced alopecia. In contrast, hair transplantation in lichen planopilaris (LPP) can be risky because it can reactivate the disease. For this reason, most hair transplant surgeons consider that LPP can be transplanted if confirmed quiescence has been demonstrated...
متن کاملLichen planus pigmentosus and lichen planopilaris.
Lichen planus is an inflammatory skin conditionwith characteristic histopathological findings thathas many clinical variants. Recently, there have been25 cases reported in the literature of lichen planuspigmentosus (LPPi) that preceded the developmentof frontal fibrosing alopecia (FFA), which is a variantof lichen planopilaris (LPP). We review the literatureregarding LPPi, LPP, and FFA and pres...
متن کاملLichen planopilaris developed during childhood*
Lichen planopilaris is a disease that appears with lymphocytic cicatricial alopecia. It is considered a follicular variant of lichen planus. The examination of affected areas shows alopecia with perifollicular erythema and scaling, revealing a predilection for hair follicles. The involvement of children is uncommon, with few reports in this population in the literature. This study presents a cl...
متن کاملAlterated integrin expression in lichen planopilaris
BACKGROUND Lichen planopilaris (LPP) is an inflammatory disease characterized by a lymphomononuclear infiltrate surrounding the isthmus and infundibulum of the hair follicle of the scalp, that evolves into atrophic/scarring alopecia. In the active phase of the disease hairs are easily plucked with anagen-like hair-roots. In this study we focused on the expression of integrins and basement membr...
متن کاملHydroxychloroquine and lichen planopilaris: efficacy and introduction of Lichen Planopilaris Activity Index scoring system.
BACKGROUND Lichen planopilaris (LPP) and its variant frontal fibrosing alopecia (FFA) are primary lymphocytic cicatricial alopecias for which there is no evidence-based therapy. OBJECTIVE We assessed the efficacy of hydroxychloroquine in active LPP and FFA using the LPP Activity Index (LPPAI), a numeric score that allows quantification of the symptoms and signs of the condition for statistica...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2018
ISSN: 0022-202X
DOI: 10.1016/j.jid.2018.03.1385